A Dual‐domain Engineered Antibody for Efficient HBV Suppression and Immune Responses Restoration

A Dual‐domain Engineered Antibody for Efficient HBV Suppression and Immune Responses Restoration

Abstract Chronic hepatitis B (CHB) remains a major public health concern because of the inefficiency of currently approved therapies in clearing the hepatitis B surface antigen (HBsAg). Antibody‐based regimens have demonstrated potency regarding virus neutralization and HBsAg clearance. However, hig...

Full description

Bibliographic Details
Main Authors: Yichao Jiang, Xiaoqing Chen, Xinya Ye, Can Wen, Tao Xu, Chao Yu, Wenjing Ning, Guosong Wang, Xinchu Xiang, Xiaomin Liu, Yalin Wang, Yuanzhi Chen, Xue Liu, Changrong Shi, Chao Liu, Quan Yuan, Yixin Chen, Tianying Zhang, Wenxin Luo, Ningshao Xia
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
antibody‐based immunotherapy
chronic hepatitis B
immune restoration
therapeutic efficacy
Online Access:https://doi.org/10.1002/advs.202305316

Internet

https://doi.org/10.1002/advs.202305316

Similar Items