Keap1-Nrf2 pathway: a key mechanism in the occurrence and development of cancer

Keap1-Nrf2 pathway: a key mechanism in the occurrence and development of cancer

The Keap1-Nrf2 signaling pathway is a major regulator of the cytoprotective response, participating in endogenous and exogenous stress caused by ROS (reactive oxygen species). Nrf2 is the core of this pathway. We summarized the literature on Keap1-Nrf2 signaling pathway and summarized the following...

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Bibliographic Details
Main Authors: Feilong Chen, Mei Xiao, Shaofan Hu, Meng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Oncology
Subjects:
Keap1
Nrf2
cancer
structure
function
transcriptional regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1381467/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1381467/full

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