GTN Enhances Antitumor Effects of Doxorubicin in TNBC by Targeting the Immunosuppressive Activity of PMN-MDSC

(1) Background: Immunosuppression is a key barrier to effective anti-cancer therapies, particularly in triple-negative breast cancer (TNBC), an aggressive and difficult to treat form of breast cancer. We investigated here whether the combination of doxorubicin, a standard chemotherapy in TNBC with g...

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Bibliographic Details
Main Authors: Nesrine Mabrouk, Cindy Racoeur, Jingxuan Shan, Aurélie Massot, Silvia Ghione, Malorie Privat, Lucile Dondaine, Elise Ballot, Caroline Truntzer, Romain Boidot, François Hermetet, Valentin Derangère, Mélanie Bruchard, Frédérique Végran, Lotfi Chouchane, François Ghiringhelli, Ali Bettaieb, Catherine Paul
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/12/3129