Regio and stereoselective synthesis of anticancer spirooxindolopyrrolidine embedded piperidone heterocyclic hybrids derived from one-pot cascade protocol
Abstract Background Spiropyrrolidine tethered piperidone heterocyclic hybrids were synthesized with complete regio- and stereoselectively in excellent yield via a tandem three-component 1,3-dipolar cycloaddition and subsequent enamine reaction in [bmim]Br. The synthesized compounds were evaluated fo...
| Main Authors: | , , , , , , , , , |
|---|---|
| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
BMC
2018-09-01
|
| סדרה: | Chemistry Central Journal |
| נושאים: | |
| גישה מקוונת: | http://link.springer.com/article/10.1186/s13065-018-0462-x |