Syntaxin 18 regulates the DNA damage response and epithelial-to-mesenchymal transition to promote radiation resistance of lung cancer

Syntaxin 18 regulates the DNA damage response and epithelial-to-mesenchymal transition to promote radiation resistance of lung cancer

Abstract Radiotherapy is an important modality in lung cancer treatment. Despite advances in treatment planning and dose delivery, patient benefit is still limited by in-field relapse and metastatic recurrence. Simultaneous application of cisplatinum-based chemotherapy leads to moderately improved o...

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Bibliographic Details
Main Authors: Clotilde Thumser-Henner, Sebastian Oeck, Sophie Kalmbach, Jan Forster, Franziska Kindl, Ali Sak, Alexander Schramm, Martin Schuler
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04978-4

Internet

https://doi.org/10.1038/s41419-022-04978-4

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