Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy

Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy

Abstract Sjögren’s disease (SjD) is a chronic autoimmune sialadenitis resulting in salivary gland hypofunction with dry mouth symptom. Previous studies showed that lysosome-associated membrane protein 3 (LAMP3) overexpression is involved in the development of salivary gland hypofunction associated w...

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Bibliographic Details
Main Authors: Hiroyuki Nakamura, Tsutomu Tanaka, Changyu Zheng, Sandra A. Afione, Blake M. Warner, Masayuki Noguchi, Tatsuya Atsumi, John A. Chiorini
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21374-2

Internet

https://doi.org/10.1038/s41598-022-21374-2

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