A method for chromatin domain partitioning based on hypergraph clustering

For many years, multi-scale models of chromatin domains, such as A/B compartments, sub-compartments, topologically associated domains (TADs), sub-TADs, and loops have been popular. However, existing methods can only identify structures at a single scale and cannot partition multi-scale structures. I...

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Bibliographic Details
Main Authors: Haiyan Gong, Sichen Zhang, Xiaotong Zhang, Yang Chen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000916