CAR-T cells neurotoxicity from consolidated practice in hematological malignancies to fledgling experience in CNS tumors: fill the gap

CAR-T cells neurotoxicity from consolidated practice in hematological malignancies to fledgling experience in CNS tumors: fill the gap

Chimeric antigen receptor (CAR-T) therapy has marked a paradigm shift in the treatment of hematological malignancies and represent a promising growing field also in solid tumors. Neurotoxicity is a well‐recognized common complication of CAR-T therapy and is at the forefront of concerns for CAR-based...

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Bibliographic Details
Main Authors: Lidia Gatto, Ilaria Ricciotti, Alicia Tosoni, Vincenzo Di Nunno, Stefania Bartolini, Lucia Ranieri, Enrico Franceschi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
CAR-T therapy
neurotoxicity
glioma
glioblastoma (GBM)
immune effector cell-associated neurotoxicity syndrome (ICANS)
ASTCT grading scale
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1206983/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1206983/full

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