Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response.

Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response.

Brucellosis, caused by facultative, intracellular Brucella spp., often results in chronic and/or lifelong infection. Therefore, Brucella must employ mechanisms to subvert adaptive immunity to cause chronic infection. B lymphocytes enhance susceptibility to infection with Brucella spp. though the mec...

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Bibliographic Details
Main Authors: Alexis S Dadelahi, Mostafa F N Abushahba, Bárbara Ponzilacqua-Silva, Catherine A Chambers, Charles R Moley, Carolyn A Lacey, Alexander L Dent, Jerod A Skyberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011672&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011672&type=printable

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