Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells

<p>Abstract</p> <p>Background</p> <p>Evidence indicates that soluble forms of amyloid-β (Aβ) are vasoactive, which may contribute to cerebrovascular dysfunction noted in patients with Alzheimer's Disease and cerebral amyloid angiopathy. The effects of soluble Aβ on...

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Bibliographic Details
Main Authors: Zipfel Gregory J, Han Byung H, Xiang Chuanxi, Dietrich Hans H, Holtzman David M
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/15