Thioredoxin Reductase 1 Is a Highly Immunogenic Cell Surface Antigen in Paracoccidioides spp., Candida albicans, and Cryptococcus neoformans

Thioredoxin Reductase 1 Is a Highly Immunogenic Cell Surface Antigen in Paracoccidioides spp., Candida albicans, and Cryptococcus neoformans

The increasing number of immunocompromised people has made invasive fungal infections more common. The antifungal armamentarium, in contrast, is limited to a few classes of drugs, with frequent toxicity and low efficacy pointing to the need for new agents. Antibodies are great candidates for novel a...

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Bibliographic Details
Main Authors: Fabiana Freire Mendes de Oliveira, Verenice Paredes, Herdson Renney de Sousa, Ágata Nogueira D’Áurea Moura, Juan Riasco-Palacios, Arturo Casadevall, Maria Sueli Soares Felipe, André Moraes Nicola
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
Cryptococcus neoformans
Candida albicans
Paracoccidioides lutzii
thioredoxin reductase
cell wall
antibodies
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02930/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02930/full

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