Oridonin Synergistically Enhances the Pro-Apoptotic Effect of Venetoclax on Acute Myeloid Leukemia Cells by Inhibiting AKT Signaling
Background: Acute myeloid leukemia (AML) is a recurrence-prone hematologic malignancy. The advent of molecularly targeted therapies provides new opportunities to enhance the effectiveness of AML treatments. Venetoclax, a selective inhibitor of the anti-apoptotic protein Bcl-2, has shown promising re...
Main Authors: | Lin Chen, Dongbei Li, Xiaoli Guo, Cheng Cheng, Xudong Wei |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2023-09-01
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Series: | Frontiers in Bioscience-Landmark |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/FBL/28/9/10.31083/j.fbl2809195 |
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