Antidepressants for the prevention of depression following first-episode psychosis (ADEPP): study protocol for a multi-centre, double-blind, randomised controlled trial

Antidepressants for the prevention of depression following first-episode psychosis (ADEPP): study protocol for a multi-centre, double-blind, randomised controlled trial

Abstract Background Depressive episodes are common after first-episode psychosis (FEP), affecting more than 40% of people, adding to individual burden, poor outcomes, and healthcare costs. If the risks of developing depression were lower, this could have a beneficial effect on morbidity and mortalit...

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Bibliographic Details
Main Authors: Edward R. Palmer, Siân Lowri Griffiths, Ben Watkins, Tyler Weetman, Ryan Ottridge, Smitaa Patel, Rebecca Woolley, Sarah Tearne, Pui Au, Eleanor Taylor, Zara Sadiq, Hareth Al-Janabi, Barnaby Major, Charlotte Marriott, Nusrat Husain, Mohammad Zia Ul Haq Katshu, Domenico Giacco, Nicholas M. Barnes, James T. R. Walters, Thomas R. E. Barnes, Max Birchwood, Richard Drake, Rachel Upthegrove
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Trials
Subjects:
Prevention
Depression
Antidepressant
Functioning
First-episode psychosis
Online Access:https://doi.org/10.1186/s13063-023-07499-3

Internet

https://doi.org/10.1186/s13063-023-07499-3

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