Detection of PLZF- RARa Fusion in Patients with Acute Promyelocytic Leukemia

Detection of PLZF- RARa Fusion in Patients with Acute Promyelocytic Leukemia

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Background and Aim: Acute promyelocytic leukemia (APL) is associated with the t(15;17) ,fusing promyelocytic leukemia (PML) and retinoic acid receptor-a (RARa) genes. This disease is uniquely sensitive to treatment with all-trans retinoic acid (ATRA) and highly responsive to conventional chemotherap...

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Bibliographic Details
Main Authors: SH Rostami, H Rahimi, B Chardooli, N Einollahi, K Alimoghadam, M Araghi, A Ghavamzadeh
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2008-08-01
Series:پیاورد سلامت
Subjects:
PLZF-RARa
PML- RARa
Acute Promyelocytic Leukemia (APL)
RT-PCR
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/13540.pdf&manuscript_id=13540

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http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/13540.pdf&manuscript_id=13540

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