Cavin-2 loss exacerbates hypoxia-induced pulmonary hypertension with excessive eNOS phosphorylation and protein nitration

Cavin-2 loss exacerbates hypoxia-induced pulmonary hypertension with excessive eNOS phosphorylation and protein nitration

Pulmonary hypertension (PH) is associated with a poor prognosis even in recent years. Caveolin-1 (CAV1), a caveolae-associated protein, is a causal gene in PH. Cavin-2, one of the other caveolae-associated proteins, forms protein complexes with CAV1 and influences each other's functions. Howeve...

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Bibliographic Details
Main Authors: Takeru Kasahara, Takehiro Ogata, Naohiko Nakanishi, Shinya Tomita, Yusuke Higuchi, Naoki Maruyama, Tetsuro Hamaoka, Satoaki Matoba
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Pulmonary hypertension
Endothelial cells
Caveolin-1
eNOS
Nitration
PKG
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023044018

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023044018

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