Surufatinib combined with photodynamic therapy induces ferroptosis to inhibit cholangiocarcinoma in vitro and in tumor models

Surufatinib combined with photodynamic therapy induces ferroptosis to inhibit cholangiocarcinoma in vitro and in tumor models

The curative effect of single therapy for advanced cholangiocarcinoma (CCA) is poor, thus investigating combined treatment strategies holds promise for improving prognosis. Surufatinib (SUR) is a novel multikinase inhibitor that has been confirmed to prolong survival of patients with advanced CCA. P...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Yun-Peng Huang, Yong-Xiang Wang, Hui Zhou, Zhong-Tao Liu, Zi-Jian Zhang, Li Xiong, Heng Zou, Yu Wen
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Frontiers Media S.A. 2024-04-01
Cyfres:Frontiers in Pharmacology
Pynciau:
ferroptosis
Photodynainic therapy
Cholangicarcinoma
GPx4
ACSL4
organoids
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fphar.2024.1288255/full

Rhyngrwyd

https://www.frontiersin.org/articles/10.3389/fphar.2024.1288255/full

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