Optimized workflow to modify microRNA expression in primary human intravascular cells

Abstract Background A comprehensive dissection of the role of microRNAs (miRNAs) in gene regulation and subsequent cell functions requires a specific and efficient knockdown or overexpression of the miRNA of interest; these are achieved by transfecting the cell of interest with a miRNA inhibitor or...

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Bibliographic Details
Main Authors: Safak Caglayan, John-Bjarne Hansen, Omri Snir
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Immunology
Subjects:
Online Access:https://doi.org/10.1186/s12865-023-00540-9