CimpleG: finding simple CpG methylation signatures
Abstract DNA methylation signatures are usually based on multivariate approaches that require hundreds of sites for predictions. Here, we propose a computational framework named CimpleG for the detection of small CpG methylation signatures used for cell-type classification and deconvolution. We show...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-023-03000-0 |