A DNA Vaccine Encoding the Full-Length Spike Protein of Beta Variant (B.1.351) Elicited Broader Cross-Reactive Immune Responses against Other SARS-CoV-2 Variants

A DNA Vaccine Encoding the Full-Length Spike Protein of Beta Variant (B.1.351) Elicited Broader Cross-Reactive Immune Responses against Other SARS-CoV-2 Variants

The SARS-CoV-2 pandemic remains an ongoing threat to global health with emerging variants, especially the Omicron variant and its sub-lineages. Although large-scale vaccination worldwide has delivered outstanding achievements for COVID-19 prevention, a declining effectiveness to a different extent i...

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Bibliographic Details
Main Authors: Gan Zhao, Zhiyu Zhang, Yuan Ding, Jiawang Hou, Ying Liu, Mengying Zhang, Cheng Sui, Limei Wang, Xin Xu, Xiaoming Gao, Zhihua Kou
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Vaccines
Subjects:
SARS-CoV-2
variant of concern (VOC)
cross-reactive immune responses
vaccine
DNA vaccine
Online Access:https://www.mdpi.com/2076-393X/11/3/513

Internet

https://www.mdpi.com/2076-393X/11/3/513

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