MicroRNA-219 Inhibits Proliferation and Induces Differentiation of Oligodendrocyte Precursor Cells after Contusion Spinal Cord Injury in Rats

MicroRNA-219 (miR-219) regulates the proliferation and differentiation of oligodendrocyte precursor cells (OPCs) during central nervous system (CNS) development. OPCs only differentiate into oligodendrocytes (OLs) in the healthy CNS, but can generate astrocytes (As) after injury. We hypothesized tha...

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Bibliographic Details
Main Authors: Fang Li, Mou-Wang Zhou, Nan Liu, Yan-Yan Yang, Hua-Yi Xing, Yao Lu, Xiao-Xie Liu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2019/9610687