Sertraline-induced reproductive toxicity in male rats: evaluation of possible underlying mechanisms

Sertraline-induced reproductive toxicity in male rats: evaluation of possible underlying mechanisms

This study was conducted to clarify the toxic effects of sertraline (SRT) on the reproductive system of male rats and to elucidate the underlying mechanisms. Rats were treated orally with SRT at doses of 5, 10, and 20 mg kg−1 for 28 consecutive days. At the end of the treatment period, sperm concent...

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Bibliographic Details
Main Authors: Ozlem Atli, Merve Baysal, Gozde Aydogan-Kilic, Volkan Kilic, Seyda Ucarcan, Burak Karaduman, Sinem Ilgin
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Asian Journal of Andrology
Subjects:
DNA damage; oxidative stress; reproductive toxicity; sertraline
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2017;volume=19;issue=6;spage=672;epage=679;aulast=

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2017;volume=19;issue=6;spage=672;epage=679;aulast=

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