Tandem mass tag-based proteomics analysis reveals the multitarget mechanisms of Phyllanthus emblica against liver fibrosis

Tandem mass tag-based proteomics analysis reveals the multitarget mechanisms of Phyllanthus emblica against liver fibrosis

Phyllanthus emblica (PE), a traditional multiethnic herbal medicine, is commonly applied to treat liver diseases. Our previous study demonstrated that aqueous extract of PE (AEPE) could alleviate carbon tetrachloride (CCl4)-induced liver fibrosis in vivo, but the underlying molecular mechanisms are...

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Bibliographic Details
Main Authors: Puyang Gong, Kehuan Yin, Xiaomin Luo, Jian Gu, Rui Tan, Yan Wu, Dapeng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Phyllanthus emblica
liver fibrosis
TMT-based proteomics
multi-target mechanism
differentially expressed proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.989995/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.989995/full

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