Therapeutic Antibody-Like Immunoconjugates against Tissue Factor with the Potential to Treat Angiogenesis-Dependent as Well as Macrophage-Associated Human Diseases

Therapeutic Antibody-Like Immunoconjugates against Tissue Factor with the Potential to Treat Angiogenesis-Dependent as Well as Macrophage-Associated Human Diseases

Accumulating evidence suggests that tissue factor (TF) is selectively expressed in pathological angiogenesis-dependent as well as macrophage-associated human diseases. Pathological angiogenesis, the formation of neovasculature, is involved in many clinically significant human diseases, notably cance...

Full description

Bibliographic Details
Main Author: Zhiwei Hu
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Antibodies
Subjects:
tissue factor
factor VII
antibodies
antibody-like immunoconjugates (ICON and L-ICON1)
solid cancer
Leukemia
age-related macular degeneration
endometriosis
rheumatoid arthritis
atherosclerosis
angiogenesis
vascular endothelial cell
cancer cell
cancer stem cell
macrophage
fibroblast
B cell
Online Access:http://www.mdpi.com/2073-4468/7/1/8

Internet

http://www.mdpi.com/2073-4468/7/1/8

Similar Items