In vivo dynamics and regulation of DNA G-quadruplex structures in mammals

Abstract G-quadruplex (G4) is a four-stranded helical DNA secondary structure formed by guanine-rich sequence folding, and G4 has been computationally predicted to exist in a wide range of species. Substantial evidence has supported the formation of endogenous G4 (eG4) in living cells and revealed i...

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Bibliographic Details
Main Authors: Ze-Hao Zhang, Sheng Hu Qian, Dengguo Wei, Zhen-Xia Chen
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-023-01074-8