An enriched environment ameliorates the reduction of parvalbumin-positive interneurons in the medial prefrontal cortex caused by maternal separation early in life

Early child maltreatment, such as child abuse and neglect, is well known to affect the development of social skills. However, the mechanisms by which such an adverse environment interrupts the development of social skills remain unelucidated. Identifying the period and brain regions that are suscept...

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Main Authors: Kanako Irie, Ken-ichi Ohta, Hidetoshi Ujihara, Chihiro Araki, Kodai Honda, Shingo Suzuki, Katsuhiko Warita, Hikari Otabi, Haruki Kumei, Shinji Nakamura, Kosuke Koyano, Takanori Miki, Takashi Kusaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1308368/full