Anti-Inflammatory Effects of Sulfated Polysaccharide from <i>Sargassum swartzii</i> in Macrophages via Blocking TLR/NF-Κb Signal Transduction

Anti-Inflammatory Effects of Sulfated Polysaccharide from <i>Sargassum swartzii</i> in Macrophages via Blocking TLR/NF-Κb Signal Transduction

This study involves enzymatic extraction of fucoidan from <i>Sargassum swartzii</i> and further purification via ion-exchange chromatography. The chemical and molecular characteristics of isolated fucoidan is evaluated concerning its anti-inflammatory potential in RAW 264.7 macrophages u...

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Bibliographic Details
Main Authors: Thilina U. Jayawardena, K. K. Asanka Sanjeewa, D. P. Nagahawatta, Hyo-Geun Lee, Yu-An Lu, A. P. J. P. Vaas, D. T. U. Abeytunga, C. M. Nanayakkara, Dae-Sung Lee, You-Jin Jeon
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Marine Drugs
Subjects:
<i>Sargassum swartzii</i>
TLR/MyD88
NF-κB
MAPK
fucoidan
Online Access:https://www.mdpi.com/1660-3397/18/12/601

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https://www.mdpi.com/1660-3397/18/12/601

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