NRAGE Confers Radiation Resistance in 2D and 3D Cell Culture and Poor Outcome in Patients With Esophageal Squamous Cell Carcinoma

NRAGE Confers Radiation Resistance in 2D and 3D Cell Culture and Poor Outcome in Patients With Esophageal Squamous Cell Carcinoma

ObjectiveThe purpose of the study is to explore the mechanism of NRAGE enhancing radioresistance of esophageal squamous cell carcinoma (ESCC) in 2D and 3D levels.MethodsStably NRAGE-overexpressed ESCC cells and 3D-printing models for ESCC cells were established. Then, cellular malignancy indexes, su...

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Bibliographic Details
Main Authors: Huandi Zhou, Guohui Wang, Zhiqing Xiao, Yu Yang, Zhesen Tian, Chen Gao, Xuetao Han, Wei Sun, Liubing Hou, Junling Liu, Xiaoying Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma
radioresistance
NRAGE
3D bio-printing
Wnt/β-catenin
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.831506/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.831506/full

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