Comprehensive and Accurate Molecular Profiling of Breast Cancer through mRNA Expression of <i>ESR1</i>, <i>PGR</i>, <i>ERBB2</i>, <i>MKI67</i>, and a Novel Proliferation Signature
Background: An accurate status determination of breast cancer biomarkers (ER, PR, HER2, Ki67) is crucial for guiding patient management. The “gold standard” for assessing these biomarkers in FFPE tissue is IHC, which faces challenges in standardization and exhibits substantial variability. In this s...
Main Authors: | Anne-Sophie Wegscheider, Joanna Gorniak, Sara Rollinson, Leanne Gough, Navdeep Dhaliwal, Agustin Guardiola, Anna Gasior, Denise Helmer, Zoe Pounce, Axel Niendorf |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-01-01
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Series: | Diagnostics |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4418/14/3/241 |
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