Dystrophin hydrophobic regions in the pathogenesis of Duchenne and Becker muscular dystrophies

Dystrophin hydrophobic regions in the pathogenesis of Duchenne and Becker muscular dystrophies

The aim of our study was to determine the role of dystrophin hydrophobic regions in the pathogenesis of Duchenne (DMD) and Becker (BMD) muscular dystrophies, by the Kyte-Doolittle scale mean hydrophobicity profile and 3D molecular models. A total of 1038 cases diagnosed with DMD or BMD with the in-f...

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Bibliographic Details
Main Authors: Yingyin Liang, Songlin Chen, Jianzong Zhu, Xiangxue Zhou, Chen Yang, Lu Yao, Cheng Zhang
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2015-05-01
Series:Biomolecules & Biomedicine
Subjects:
DMD
BMD
dystrophin
Kyte-Doolittle scale mean hydrophobicity profile
3D model
genotype–phenotype analysis
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/300

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https://www.bjbms.org/ojs/index.php/bjbms/article/view/300

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