Human Cytomegalovirus Reduces Endothelin-1 Expression in Both Endothelial and Vascular Smooth Muscle Cells

Human Cytomegalovirus Reduces Endothelin-1 Expression in Both Endothelial and Vascular Smooth Muscle Cells

Human cytomegalovirus (HCMV) is an opportunistic pathogen that has been implicated in the pathogenesis of atherosclerosis. Endothelin-1 (ET-1), a potent vasoconstrictive peptide, is overexpressed and strongly associated with many vasculopathies. The main objective of this study was to investigate wh...

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Bibliographic Details
Main Authors: Koon-Chu Yaiw, Abdul-Aleem Mohammad, Chato Taher, Huanhuan Leah Cui, Helena Costa, Ourania N. Kostopoulou, Masany Jung, Alice Assinger, Vanessa Wilhelmi, Jiangning Yang, Klas Strååt, Afsar Rahbar, John Pernow, Cecilia Söderberg-Nauclér
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Microorganisms
Subjects:
human cytomegalovirus
immediate-early
endothelin-1
endothelial cells
smooth muscle cells
Online Access:https://www.mdpi.com/2076-2607/9/6/1137

Internet

https://www.mdpi.com/2076-2607/9/6/1137

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