TMPE Derived from Saffron Natural Monoterpene as Cytotoxic and Multidrug Resistance Reversing Agent in Colon Cancer Cells

TMPE Derived from Saffron Natural Monoterpene as Cytotoxic and Multidrug Resistance Reversing Agent in Colon Cancer Cells

Terpenes constitute one of the largest groups of natural products. They exhibit a wide range of biological activities including antioxidant, anticancer, and drug resistance modulating properties. Saffron extract and its terpene constituents have been demonstrated to be cytotoxic against various type...

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Bibliographic Details
Main Authors: Kamila Środa-Pomianek, Anna Palko-Łabuz, Andrzej Poła, Mirosława Ferens-Sieczkowska, Olga Wesołowska, Agata Kozioł
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
monoterpene
saffron
β-cyclocitral
anticancer activity
multidrug resistance (MDR) reversal
ABCB1 transporter (P-glycoprotein)
Online Access:https://www.mdpi.com/1422-0067/21/20/7529

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https://www.mdpi.com/1422-0067/21/20/7529

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