Pathogenic Insights into DNA Mismatch Repair (MMR) Genes–Proteins and Microsatellite Instability: Focus on Adrenocortical Carcinoma and Beyond

Pathogenic Insights into DNA Mismatch Repair (MMR) Genes–Proteins and Microsatellite Instability: Focus on Adrenocortical Carcinoma and Beyond

DNA damage repair pathways, including mismatch repair (MMR) genes, are prone to carcinoma development in certain patients. The assessment of the MMR system is widely recognized as part of strategies concerning solid tumors (defective MMR cancers), especially MMR proteins (through immunohistochemistr...

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Bibliographic Details
Main Authors: Mara Carsote, Ionut Florin Turturea, Maria Roxana Turturea, Ana Valea, Claudiu Nistor, Ancuta-Augustina Gheorghisan-Galateanu
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Diagnostics
Subjects:
adrenocortical carcinoma
MMR gene
MMR protein
microsatellite instability
endocrine
Lynch syndrome
Online Access:https://www.mdpi.com/2075-4418/13/11/1867

Internet

https://www.mdpi.com/2075-4418/13/11/1867

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