Frequency changes in HLA‐I alleles: A marker to guide immunotherapy in lung adenocarcinoma patients and its relationship with tumor mutational burden and PD‐L1 expression

Frequency changes in HLA‐I alleles: A marker to guide immunotherapy in lung adenocarcinoma patients and its relationship with tumor mutational burden and PD‐L1 expression

Abstract Background The aim of the study was to investigate differences in HLA‐I alleles between lung adenocarcinoma patients and healthy controls and determine their association with PD‐L1 expression and tumor mutational burden (TMB) to understand the mechanism underlying lung adenocarcinoma suscep...

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Bibliographic Details
Main Authors: Xuanpeng Wu, Hao Wang, Fei Xue, Tao Jiang, Nanzheng Chen, Tianju Wang, Yong Zhang, Guangjian Zhang, Junke Fu, Qifei Wu
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Thoracic Cancer
Subjects:
allele
human leukocyte antigen
lung adenocarcinoma
PD‐L1
TMB
Online Access:https://doi.org/10.1111/1759-7714.14939

Internet

https://doi.org/10.1111/1759-7714.14939

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