Crosstalk of Histone and RNA Modifications Identified a Stromal-Activated Subtype with Poor Survival and Resistance to Immunotherapy in Gastric Cancer

Crosstalk of Histone and RNA Modifications Identified a Stromal-Activated Subtype with Poor Survival and Resistance to Immunotherapy in Gastric Cancer

Emerging evidence has revealed the pivotal role of epigenetic modifications in shaping the tumor microenvironment (TME). However, crosstalk between different modification types and their clinical relevance in cancers remain largely unexplored. In this study, using ChIP/MeRIP-seq data of seven human...

Full description

Bibliographic Details
Main Authors: Cheng Yuan, Junchang Zhang, Cuncan Deng, Yujian Xia, Bo Li, Sijun Meng, Xinghan Jin, Lvjia Cheng, Huafu Li, Changhua Zhang, Yulong He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
gastric cancer
histone modification
m6A
tumor microenvironment
prognosis
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.868830/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.868830/full

Similar Items