Expression quantitative trait locus studies in the era of single-cell omics

Genome-wide association studies have revealed that the regulation of gene expression bridges genetic variants and complex phenotypes. Profiling of the bulk transcriptome coupled with linkage analysis (expression quantitative trait locus (eQTL) mapping) has advanced our understanding of the relations...

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Bibliographic Details
Main Authors: Jie Luo, Xinyi Wu, Yuan Cheng, Guang Chen, Jian Wang, Xijiao Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1182579/full