Detection of BRCA1 Pathogenic Variant in a 24-Year-Old Endometrial Cancer Patient: Risks of Several Hereditary Tumor Syndromes Assessed Using Germline Multigene Panel Testing

Detection of BRCA1 Pathogenic Variant in a 24-Year-Old Endometrial Cancer Patient: Risks of Several Hereditary Tumor Syndromes Assessed Using Germline Multigene Panel Testing

A 24-year-old woman suspected of Lynch syndrome was found to carry a BRCA1 pathogenic variant, based on germline multigene panel testing (MGPT). The patient was diagnosed with endometrial carcinoma and underwent modified radical hysterectomy, bilateral salpingo-oophorectomy, pelvic lymphadenectomy,...

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Bibliographic Details
Main Authors: Xiaofei Wang, Keika Kaneko, Hiromi Arakawa, Eri Habano, Makiko Omi, Eri Nakashima, Hiroshi Kawachi, Akiko Tonooka, Kohei Omatsu, Hidetaka Nomura, Mayu Yunokawa, Hiroyuki Kanao, Shunji Takahashi, Takeshi Nakajima, Arisa Ueki
Format: Article
Language:English
Published: Karger Publishers 2022-08-01
Series:Case Reports in Oncology
Subjects:
endometrial cancer
brca1
multigene panel testing
hereditary breast and ovarian
cancer syndrome
lynch syndrome
Online Access:https://beta.karger.com/Article/FullText/525941

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https://beta.karger.com/Article/FullText/525941

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