Fast gene transfer into the adult zebrafish brain by herpes simplex virus 1 (HSV-1) and electroporation: methods and optogenetic applications

The zebrafish has various advantages as a model organism to analyze the structure and function of neural circuits but efficient viruses or other tools for fast gene transfer are lacking. We show that transgenes can be introduced directly into the adult zebrafish brain by herpes simplex type I viruse...

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Bibliographic Details
Main Authors: Ming eZou, Paul eDe Koninck, Rachael L. Neve, Rainer W Friedrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00041/full