miR-518b Enhances Human Trophoblast Cell Proliferation Through Targeting Rap1b and Activating Ras-MAPK Signal

miR-518b Enhances Human Trophoblast Cell Proliferation Through Targeting Rap1b and Activating Ras-MAPK Signal

Preeclampsia is a pregnancy-specific complication defined as newly onset gestational hypertension and proteinuria. Deficiency in placental development is considered as the predominant cause of preeclampsia. Our previous study found that the expression of miR-518b increased significantly in the preec...

Full description

Bibliographic Details
Main Authors: Ming Liu, Yongqing Wang, Huifen Lu, Hao Wang, Xiaoming Shi, Xuan Shao, Yu-xia Li, Yangyu Zhao, Yan-Ling Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Endocrinology
Subjects:
miR-518b
Rap1b
trophoblast
proliferation
preeclampsia
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00100/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00100/full

Similar Items