miR-518b Enhances Human Trophoblast Cell Proliferation Through Targeting Rap1b and Activating Ras-MAPK Signal
Preeclampsia is a pregnancy-specific complication defined as newly onset gestational hypertension and proteinuria. Deficiency in placental development is considered as the predominant cause of preeclampsia. Our previous study found that the expression of miR-518b increased significantly in the preec...
Main Authors: | Ming Liu, Yongqing Wang, Huifen Lu, Hao Wang, Xiaoming Shi, Xuan Shao, Yu-xia Li, Yangyu Zhao, Yan-Ling Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-03-01
|
Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fendo.2018.00100/full |
Similar Items
-
Nuclear Factor-Kappa B-induced miRNA-518a-5p represses trophoblast cell migration and invasion by the Nuclear Factor-Kappa B pathway
by: XING PENG, et al.
Published: (2023-05-01) -
Decreto 518 de 11 de janeiro de 1898
by: GT Histedbr
Published: (2012-06-01) -
Prognostic and immunological role of Ras-related protein Rap1b in pan-cancer
by: Guoliang Cui, et al.
Published: (2021-01-01) -
Small GTP‐binding protein Rap1 mediates EGF and HB‐EGF signaling and modulates EGF receptor expression in HTR‐8/SVneo extravillous trophoblast cells
by: Mikihiro Yoshie, et al.
Published: (2023-01-01) -
Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy
by: Zhang M, et al.
Published: (2018-05-01)