May critical molecular cross-talk between indoleamine 2,3-dioxygenase (IDO) and arginase during human aging be targets for immunosenescence control?

Abstract Background This study aimed to identify novel plasma metabolic signatures with possible clinical relevance during the aging process. A biochemical quantitative phenotyping platform, based on targeted electrospray ionization tandem mass spectrometry technology, was used for the identificatio...

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Bibliographic Details
Main Authors: Ismael Dale Cotrim Guerreiro da Silva, Dirce Maria Lobo Marchioni, Antonio Augusto Ferreira Carioca, Valquiria Bueno, Gisele Wally Braga Colleoni
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-021-00244-x