Light-field flow cytometry for high-resolution, volumetric and multiparametric 3D single-cell analysis

Abstract Imaging flow cytometry (IFC) combines flow cytometry and fluorescence microscopy to enable high-throughput, multiparametric single-cell analysis with rich spatial details. However, current IFC techniques remain limited in their ability to reveal subcellular information with a high 3D resolu...

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Bibliographic Details
Main Authors: Xuanwen Hua, Keyi Han, Biagio Mandracchia, Afsane Radmand, Wenhao Liu, Hyejin Kim, Zhou Yuan, Samuel M. Ehrlich, Kaitao Li, Corey Zheng, Jeonghwan Son, Aaron D. Silva Trenkle, Gabriel A. Kwong, Cheng Zhu, James E. Dahlman, Shu Jia
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46250-7