Network Pharmacology-Based Strategy for the Investigation of the Anti-Osteoporosis Effects and Underlying Mechanism of Zhuangguguanjie Formulation

Network Pharmacology-Based Strategy for the Investigation of the Anti-Osteoporosis Effects and Underlying Mechanism of Zhuangguguanjie Formulation

As the society is aging, the increasing prevalence of osteoporosis has generated huge social and economic impact, while the drug therapy for osteoporosis is limited due to multiple targets involved in this disease. Zhuangguguanjie formulation (ZG) is extensively used in the clinical treatment of bon...

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Bibliographic Details
Main Authors: Wang Gong, Xingren Chen, Tianshu Shi, Xiaoyan Shao, Xueying An, Jianghui Qin, Xiang Chen, Qing Jiang, Baosheng Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pharmacology
Subjects:
osteoporosis
Zhuangguguanjie
network pharmacology
PI3K/AKT
mTOR/S6K1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.727808/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.727808/full

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