Comparative glycosylation mapping of plasma-derived and recombinant human factor VIII.

Comparative glycosylation mapping of plasma-derived and recombinant human factor VIII.

Human coagulation factor VIII (FVIII) is a key co-factor in the clotting cascade, the deficiency of which leads to Hemophilia A. Human plasma-derived (pdFVIII) and recombinant FVIII (rFVIII) had been used as effective products to prevent and treat bleeding episodes. Both FVIII products share identic...

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Bibliographic Details
Main Authors: Jingyao Qu, Cheng Ma, Xiao-Qian Xu, Min Xiao, Junping Zhang, Dong Li, Ding Liu, Barbara A Konkle, Carol H Miao, Lei Li, Weidong Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233576

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https://doi.org/10.1371/journal.pone.0233576

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