MPTAC Determines APP Fragmentation via Sensing Sulfur Amino Acid Catabolism

MPTAC Determines APP Fragmentation via Sensing Sulfur Amino Acid Catabolism

Summary: Metabolic disorder has been suggested to underlie Alzheimer’s disease (AD). However, the decisive molecular linkages remain unclear. We discovered that human Molybdopterin Synthase Associating Complex, MPTAC, promotes sulfur amino acid catabolism to prevent oxidative damage from excess sulf...

Full description

Bibliographic Details
Main Authors: Tamaki Suganuma, Selene K. Swanson, Madelaine Gogol, Timothy J. Garrett, Juliana Conkright-Fincham, Laurence Florens, Michael P. Washburn, Jerry L. Workman
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718310908

Internet

http://www.sciencedirect.com/science/article/pii/S2211124718310908

Similar Items