Tumor necrosis factor superfamily in multiple sclerosis: from pathology to therapeutic implications
Tumor necrosis factor (TNF) is a key player in multiple sclerosis pathology. TNF signaling is dually regulated by antagonist groups of actors: TNFR1, mediating proinflammatory effects and synaptopathy, CD40L-CD40 dyad, crucial for blood-brain barrier breakdown and facilitation of recruitment of inf...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2023-05-01
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Series: | Bleeding, Thrombosis and Vascular Biology |
Subjects: | |
Online Access: | https://btvb.org/btvb/article/view/66 |