Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits

Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits

Abstract Background Buprenorphine is one of the most used analgesics for postoperative pain in rabbits. The recommended dose in rabbits (0.01–0.05 mg/kg) is the same for intravenous (IV), intramuscular (IM), and subcutaneous (SC) administration, despite lack of pharmacokinetic data. Five male and fi...

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Bibliographic Details
Main Authors: Raad Askar, Elin Fredriksson, Elin Manell, Mikael Hedeland, Ulf Bondesson, Simon Bate, Lena Olsén, Patricia Hedenqvist
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Veterinary Research
Subjects:
NZW rabbit
Buprenorphine bioavailability
Administration routes
Opioid pharmacokinetics
Online Access:http://link.springer.com/article/10.1186/s12917-020-02618-7

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http://link.springer.com/article/10.1186/s12917-020-02618-7

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