Simplified method to predict mutual interactions of human transcription factors based on their primary structure.

BACKGROUND: Physical interactions between transcription factors (TFs) are necessary for forming regulatory protein complexes and thus play a crucial role in gene regulation. Currently, knowledge about the mechanisms of these TF interactions is incomplete and the number of known TF interactions is li...

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Bibliographic Details
Main Authors: Sebastian Schmeier, Boris Jankovic, Vladimir B Bajic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3130058?pdf=render