Theoretical minimal RNA rings mimick molecular evolution before tRNA-mediated translation: codon-amino acid affinities increase from early to late RNA rings

Nucleotide affinities for noncovalent interactions with amino acids produce associations between mRNAs and cognate peptides, potentially regulating ribosomal translation. Correlations between nucleotide affinities and residue hydrophobicity are explored for 25 theoretical minimal RNA rings, 22 nucle...

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Bibliographic Details
Main Authors: Demongeot, Jacques, Seligmann, Hervé
Format: Article
Language:English
Published: Académie des sciences 2020-06-01
Series:Comptes Rendus Biologies
Subjects:
Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.1/