Quantitative assessment of cell population diversity in single-cell landscapes.

Single-cell RNA sequencing (scRNA-seq) has become a powerful tool for the systematic investigation of cellular diversity. As a number of computational tools have been developed to identify and visualize cell populations within a single scRNA-seq dataset, there is a need for methods to quantitatively...

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Bibliographic Details
Main Authors: Qi Liu, Charles A Herring, Quanhu Sheng, Jie Ping, Alan J Simmons, Bob Chen, Amrita Banerjee, Wei Li, Guoqiang Gu, Robert J Coffey, Yu Shyr, Ken S Lau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006687