CLEC5A regulates Japanese encephalitis virus-induced neuroinflammation and lethality.

CLEC5A/MDL-1, a member of the myeloid C-type lectin family expressed on macrophages and neutrophils, is critical for dengue virus (DV)-induced hemorrhagic fever and shock syndrome in Stat1⁻/⁻ mice and ConA-treated wild type mice. However, whether CLEC5A is involved in the pathogenesis of viral encep...

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Main Authors: Szu-Ting Chen, Ren-Shyan Liu, Ming-Fang Wu, Yi-Ling Lin, Se-Yi Chen, David Tat-Wei Tan, Teh-Ying Chou, I-Shuen Tsai, Lei Li, Shie-Liang Hsieh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3334897?pdf=render